
Grapes contain beneficial compounds called flavonoids, which are phytonutrients that give the vibrant purple color to grapes, grape juice and red wine; the stronger the color, the higher the concentration of flavonoids.
These flavonoid compounds include quercitin, as well as a second flavonoid-type compound (falling into the chemical category of stilbenes)called resveratrol. Both compounds appear to decrease the risk of heart disease by:
- Reducing platelet clumping and harmful blood clots
- Protecting LDL cholesterol from the free radical damage that initiates LDL's artery-damaging actions
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Grapes and products made from grapes, such as wine and grape juice, may protect the French from their high-fat diets. Diets high in saturated fats like butter and lard, and lifestyle habits like smoking are risk factors for heart disease. Yet, French people with these habits have a lower risk of heart attack than Americans do. One clue that may help explain this "French paradox" is their frequent consumption of grapes and red wines.
According to researchers at the University of Wisconsin School of Medicine, patients with narrowing of the coronary arteries who drank purple grape juice daily for eight weeks showed significant improvement in their arterial function. The study is published in the September issue of The American Journal of Cardiology. It looked at the effect of drinking purple grape juice on flow mediated vaso-dilation, a measurement of the ability of the artery to relax and expand to accommodate increased blood flow. This represents a good gauge for measuring general arterial health, and the arteries of patients with vascular coronary disease typically do not relax well.
Research presented at the 226th national meeting of the American Chemical Society provides yet another explanation for red wine's cardio-protective effects-phytonutrients that help lower cholesterol called saponins. A plant protective agent found in the grapes' waxy skin, which dissolves into the wine during its fermentation process, saponins are believed to bind to and prevent the absorption of cholesterol and are also known to settle down inflammation pathways, an effect that could have implications in not only heart disease, but cancer. The research team, led by Andrew Waterhouse, PhD, from the University of California, Davis, thinks that alcohol may make the saponins more soluble and thus more available in wine.
Resveratrol, a flavonoid found in grapes, red wine and peanuts, can improve blood flow in the brain by 30%, thus greatly reducing the risk of stroke, according to the results of an animal study published in the Journal of Agricultural and Food Chemistry.
While studies show red wine offers numerous protective benefits, grape juice also provides the majority of these effects without the risks of alcohol consumption, which, if excessive can lead to accidents, liver problems, higher blood pressure, heart arrhythmias-and alcoholism.
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